The noradrenaline-dopamine interaction in the rat medial prefrontal cortex studied by multi-probe microdialysis.

@article{Kawahara2001TheNI,
  title={The noradrenaline-dopamine interaction in the rat medial prefrontal cortex studied by multi-probe microdialysis.},
  author={Hiroshi Kawahara and Yukie Kawahara and Ben H. C. Westerink},
  journal={European journal of pharmacology},
  year={2001},
  volume={418 3},
  pages={177-86}
}
Multi-probe microdialysis was used to investigate the interaction between the release of noradrenaline and dopamine in the medial prefrontal cortex. Retrograde microdialysis was used to stimulate or inhibit the activity of the locus coeruleus for a restricted period of time, and the response of extracellular noradrenaline and dopamine in the ipsilateral and contralateral medial prefrontal cortex was recorded with microdialysis probes. Infusion of clonidine into the locus coeruleus (100 microM… CONTINUE READING

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