The nonfermentable dietary fiber hydroxypropyl methylcellulose modulates intestinal microbiota.

@article{Cox2013TheND,
  title={The nonfermentable dietary fiber hydroxypropyl methylcellulose modulates intestinal microbiota.},
  author={Laura M. Cox and Ilseung Cho and Scott Andrew Young and William Henry Kerr Anderson and Bartholomew J Waters and Shao-Ching Hung and Zhan Gao and Douglas Mahana and Monika Bihan and Alexander V. Alekseyenko and Barbara A. Meth{\'e} and Martin J. Blaser},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2013},
  volume={27 2},
  pages={
          692-702
        }
}
Diet influences host metabolism and intestinal microbiota; however, detailed understanding of this tripartite interaction is limited. To determine whether the nonfermentable fiber hydroxypropyl methylcellulose (HPMC) could alter the intestinal microbiota and whether such changes correlated with metabolic improvements, C57B/L6 mice were normalized to a high-fat diet (HFD), then either maintained on HFD (control), or switched to HFD supplemented with 10% HPMC, or a low-fat diet (LFD). Compared to… CONTINUE READING
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