The non-enzymic glycosylation of bovine lens proteins by glucosamine and its inhibition by aspirin, ibuprofen and glutathione.

@article{Ajiboye1989TheNG,
  title={The non-enzymic glycosylation of bovine lens proteins by glucosamine and its inhibition by aspirin, ibuprofen and glutathione.},
  author={R. Ajiboye and J. Harding},
  journal={Experimental eye research},
  year={1989},
  volume={49 1},
  pages={
          31-41
        }
}
  • R. Ajiboye, J. Harding
  • Published 1989
  • Chemistry, Medicine
  • Experimental eye research
  • Cataract is a long-term complication of diabetes mellitus. Diabetics have increased glucosamine levels and it is possible that the non-enzymic glycosylation of the lens structural proteins by glucosamine induces conformational changes in the lens that contribute to cataract formation. Aspirin and aspirin-like analgesics may protect against glycosylation. In this paper the binding of glucosamine to bovine lens proteins and the effects of aspirin, paracetamol and ibuprofen on this reaction were… CONTINUE READING

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