The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.

@article{Shilling2000TheNA,
  title={The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.},
  author={Ann Shilling and David Edward Williams},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={2000},
  volume={74 4},
  pages={187-94}
}
In order to satisfy government mandates, numerous studies have been performed categorizing potential endocrine disrupting chemicals as (anti)estrogens or (anti)androgens. We report here that dihydrotestosterone (DHT), a potent, non-aromatizable androgen receptor agonist, induces antiestrogenic responses through direct and/or indirect modulation of vitellogenin (Vg), steroid hormone and total cytochrome P450 levels. DHT and two weak, aromatizable androgens, DHEA and androstenedione (0.05-50 mg… CONTINUE READING

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