The non-MHC transplantation antigens: neither weak nor minor.

The existence of minor histocompatibility (mH) antigens is implied by the very naming of the major histocompatibility antigens. Grafts exchanged between individuals matched at the major histocompatibility complex (MHC) (which encodes the antigens that produce rapid graft rejection) are rejected, albeit at a somewhat slower pace than MHC grafts. There are… CONTINUE READING