The nomadic engram: overtraining eliminates the impairment of discriminative avoidance behavior produced by limbic thalamic lesions.

@article{Hart1997TheNE,
  title={The nomadic engram: overtraining eliminates the impairment of discriminative avoidance behavior produced by limbic thalamic lesions.},
  author={Marcus Hart and Amy Poremba and Michael Gabriel},
  journal={Behavioural brain research},
  year={1997},
  volume={82 2},
  pages={169-77}
}
Combined lesions of the medial dorsal and anterior thalamic nuclei severely impair the acquisition of discriminative avoidance behavior, wherein rabbits learn to prevent foot-shock by stepping after a tone conditional stimulus (CS+), and they learn to ignore a different tone (CS-) that does not signal foot-shock. Neurons in these thalamic nuclei exhibit… CONTINUE READING