The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability

@inproceedings{Haas2018TheNB,
  title={The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability},
  author={P. C. A. de Haas and Stephanie S M H H{\"o}hn and Aurelia R. Honerkamp-Smith and Julius B. Kirkegaard and Raymond E. Goldstein},
  booktitle={PLoS biology},
  year={2018}
}
Variability is emerging as an integral part of development. It is therefore imperative to ask how to access the information contained in this variability. Yet most studies of development average their observations and, discarding the variability, seek to derive models, biological or physical, that explain these average observations. Here, we analyse this variability in a study of cell sheet folding in the green alga Volvox, whose spherical embryos turn themselves inside out in a process sharing… CONTINUE READING
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