The nodes of Ranvier

@article{Hess1952TheNO,
  title={The nodes of Ranvier},
  author={A Hess and John Zachary Young},
  journal={Proceedings of the Royal Society of London. Series B - Biological Sciences},
  year={1952},
  volume={140},
  pages={301 - 320}
}
  • A. Hess, J. Young
  • Published 20 November 1952
  • Materials Science, Medicine
  • Proceedings of the Royal Society of London. Series B - Biological Sciences
At a node of Ranvier the axon is reduced in diameter; on the largest mammalian fibres the reduction is to less than half of the internodal diameter. The axoplasm at the node has optical properties different from the internodal axoplasm, but there is no visible transverse boundary across it. The length of the portion of axon left uncovered at the node is less than 0·5μ in the largest mammalian fibres; it is somewhat greater on the smaller fibres. The area of the cylinder of axon membrane exposed… 
Differences between the nodes of Ranvier of large and small diameter fibres in the P.N.S.
  • C. Raine
  • Chemistry, Medicine
    Journal of neurocytology
  • 1982
TLDR
The picture which emerges from this study is that the nodal apparatus might have orientation and structural stability which contribute to its efficiency as an electrogenic pump and is structurally distinct in small and large diameter fibres.
Closely Spaced Nodes of Ranvier in the Teleost Brain
TLDR
During a study of the oculomotor nucleus of the spiny boxfish Chilomycterus with the electron microscope, I have made numerous observations of fine myelinated fibres with internodes less than 20 µm long and occasionally approximately 5 µmLong.
Minimizing the caliber of myelinated axons by means of nodal constrictions.
TLDR
It is found that there is an optimal extent of nodal constriction which minimizes the internodal axon caliber that is required to achieve a given target conduction velocity, and it is shown that this is sensitive to the precise geometry of the axon and myelin sheath in the flanking paranodal regions.
Ultrastructure of the nodes of Ranvier and their surrounding structures in the central nervous system
  • J. Metuzals
  • Chemistry, Medicine
    Zeitschrift für Zellforschung und Mikroskopische Anatomie
  • 2004
TLDR
The concept of nodal apparatus is introduced as a working hypothesis, which consists of the node, terminal compartments of the glia-satellite cell, the perinodal matrix, and the surrounding glia and nervous structures, which may be involved in the nodal activities.
The node of Ranvier in CNS pathology
TLDR
The principles by which the node of Ranvier operates and its molecular structure are reviewed, and thus how defects at the node and paranode contribute to neurological disorders are explained.
The length and diameter of the node of Ranvier.
  • F. T. Dun
  • Computer Science, Medicine
    IEEE transactions on bio-medical engineering
  • 1970
TLDR
The present analysis, which makes use of the transmission-line theory, shows that both the length and the diameter of the node are definitely related to the fiber diameter, even though these relations are not linear ones.
The Fine Anatomy of the Optic Nerve of Anurans—An Electron Microscope Study
  • H. Maturana
  • Biology, Medicine
    The Journal of biophysical and biochemical cytology
  • 1960
TLDR
The mode of ending of the myelin layers at the nodes of Ranvier and the spiral disposition of theMyelin layers indicate that myelination of these fibers occurs by a process similar to that of peripheral nerves.
Functional Organization of the Nodes of Ranvier
TLDR
This chapter reviews the molecular architecture of the nodes of Ranvier and indicates that a molecular dialogue between myelinating glial cells and axons results in the local differentiation of their complementary cellular domains.
MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS
TLDR
Electrophysiological data indicate that typical nodes in proximal regions of anteriorly and posteriorly running segments actively generate spikes, whereas large distal nodes are inactive and act as a series capacity.
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