The nk model and population genetics.

  title={The nk model and population genetics.},
  author={John J. Welch and David J Waxman},
  journal={Journal of theoretical biology},
  volume={234 3},
The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis. To examine these claims, an infinite-allele approximation is introduced. In this limit, it is shown that… CONTINUE READING