The new generation of antiepileptic drugs: advantages and disadvantages.

  title={The new generation of antiepileptic drugs: advantages and disadvantages.},
  author={Emilio Perucca},
  journal={British journal of clinical pharmacology},
  volume={42 5},
  • Emilio Perucca
  • Published 1996 in British journal of clinical pharmacology
1. After a hiatus of over 20 years, several new antiepileptic drugs (vigabatrin, lamotrigine, gabapentin, oxcarbazepine, topiramate, felbamate, zonisamide and tiagabine) have reached or approached the registration phase. 2. Compared with older agents, many new drugs exhibit simpler pharmacokinetics. This is especially true for vigabatrin and gabapentin, which are renally eliminated and have a low interaction potential. 3. Unlike most of the older agents, vigabatrin, lamotrigine, gabapentin and… CONTINUE READING
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