The new chemicals process at the Environmental Protection Agency (EPA): structure-activity relationships for hazard identification and risk assessment.

@article{Wagner1995TheNC,
  title={The new chemicals process at the Environmental Protection Agency (EPA): structure-activity relationships for hazard identification and risk assessment.},
  author={Priv.-Doz. Dr. Michael Wagner and J Vincent Nabholz and Rebekah J. Kent},
  journal={Toxicology letters},
  year={1995},
  volume={79 1-3},
  pages={67-73}
}
Section 5 of the Toxic Substances Control Act (TSCA) does not require any toxicity testing as a prerequisite for submission of a Premanufacturing Notice (PMN) for a new chemical. In order to compensate for the lack of actual test data, a process involving structure-activity relationships (SAR) for assessing hazard potential was constructed. The hazard… CONTINUE READING