The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo.

@article{Polenghi2007TheNP,
  title={The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo.},
  author={Alessandra Polenghi and Fleur Bossi and Fabio Fischetti and Paolo Durigutto and Anna Cabrelle and Nicola Tamassia and Marco A Cassatella and Cesare Montecucco and Francesco Saverio Tedesco and Marina de Bernard},
  journal={Journal of immunology},
  year={2007},
  volume={178 3},
  pages={1312-20}
}
Helicobacter pylori induces an acute inflammatory response followed by a chronic infection of the human gastric mucosa characterized by infiltration of neutrophils/polymorphonuclear cells (PMNs) and mononuclear cells. The H. pylori neutrophil-activating protein (HP-NAP) activates PMNs, monocytes, and mast cells, and promotes PMN adherence to the endothelium… CONTINUE READING