The neuroscience of grasping

  title={The neuroscience of grasping},
  author={Umberto Castiello},
  journal={Nature Reviews Neuroscience},
  • U. Castiello
  • Published 1 September 2005
  • Psychology, Biology
  • Nature Reviews Neuroscience
People have always been fascinated by the exquisite precision and flexibility of the human hand. When hand meets object, we confront the overlapping worlds of sensorimotor and cognitive functions. We reach for objects, grasp and lift them, manipulate them and use them to act on other objects. This review examines one of these actions — grasping. Recent research in behavioural neuroscience, neuroimaging and electrophysiology has the potential to reveal where in the brain the process of grasping… 

Grasping in Primates : Mechanics and Neural Basis

This work analyzes the specific time points of kinematic data of grasping and investigates its relationship with the activity of M1 neurons, and defines a synergy as a low dimensional representation of the kinematics variables that conform to the grasping.

Precision grasping in humans: from motor control to cognition

Studying the human visual cortex for improving prehension capabilities in robotics

This work proposes the outline of a model of visionbased grasp planning that differentiates from the previous ones in that it is the first to rest mainly, if not exclusively, on human physiology.

Interactions Between Cortical Areas During Skilled Grasp and Modulation by Brain Stimulation

New advances have shown it is possible to study corticocortical interactions during different task contexts and sheds new light on how brain areas are integrated in a dynamic network for controlling grasping actions.

Choice of Contact Points Modulates Sensorimotor Cortical Interactions for Dexterous Manipulation

It is concluded that the relative contribution of memory and online feedback based on whether contact points are constrained or unconstrained modulates sensorimotor cortical interactions for dexterous manipulation.

Dexterous Object Manipulation Requires Context-Dependent Sensorimotor Cortical Interactions in Humans

It is suggested that the relative contribution of memory and online feedback modulates sensorimotor cortical interactions for dexterous manipulation in constrained grasping and unconstrained grasping.

Vision-Based Grasping, Where Robotics Meets Neuroscience

The final goal of the proposal is to mimic, in a robotic setup, the coordination between sensory, associative and motor cortex of the human brain in vision-based grasping actions.

The Motor Control of Hand Movements in the Human Brain: Toward the Definition of a Cortical Representation of Postural Synergies

The organization of the brain network that controls hand posture in humans is reviewed and preliminary results of a functional Magnetic Resonance Imaging (fMRI) on the encoding of synergies at a cortical level to control hand postures in humans are presented.



Neural features of the reach and grasp.

The relationship amongst those neuronal substrates of action and the behavioral components of a movement are discussed, based upon neurophysiological data, and a novel view of reaching and grasping is proposed.

Cortical mechanism for the visual guidance of hand grasping movements in the monkey: A reversible inactivation study.

The results of this study indicate the crucial role of the ventral premotor cortex in visuomotor transformations for grasping movements and provide strong support for the notion that distal and proximal movement organization relies upon distinct cortical circuits.

A cortico-cortical mechanism mediating object-driven grasp in humans.

A cortico-cortical mechanism subserving the transformation from the geometrical properties of an object to the outputs from motor cortex before grasp that is specific for object-driven movements is demonstrated.

Hand kinematics during reaching and grasping in the macaque monkey

Monkey hand postural synergies during reach-to-grasp in the absence of vision of the hand and object.

Hand shaping during the reach occurred without vision of the hand or object, and hand kinematics were not dependent on grasp force, implying that the kinematic of reach-to-grasp and grasp force are controlled independently.

Changes in rCBF during grasping in humans examined by PET

Grasping specifically increased the rCBF in the fields located in the bilateral premotor area, the posterior parietal area and the prefrontal area, which indicates that PMA, PPA and PFA might be key structures for the performance of grasping movements.

Deficit of hand preshaping after muscimol injection in monkey parietal cortex

The results suggest that area AIP plays a crucial role in the visual guidance of goal-directed hand movements.

Posterior parietal cortex control of reach‐to‐grasp movements in humans

Results demonstrated differential activation of the parietal cortices according to the number of potential targets to be taken into account before movement initiation and the variability of target location.