The neuroscience of addiction

@article{Volkow2005TheNO,
  title={The neuroscience of addiction},
  author={Nora D. Volkow and Ting-kai Li},
  journal={Nature Neuroscience},
  year={2005},
  volume={8},
  pages={1429-1430}
}
The burden of substance abuse and addiction to society is enormous, with an estimated annual economic impact in the United States of approximately half a trillion dollars arising from medical consequences, loss of productivity, accidents and crime1. The impact of drugs and alcohol on children is particularly problematic, as adolescents are significantly more vulnerable than adults to substance abuse and to addiction2. Also, because many of the molecular targets affected by drugs are involved… 

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