The neuropsychiatry of megaloblastic anaemia.

  title={The neuropsychiatry of megaloblastic anaemia.},
  author={Simon D. Shorvon and M. W. P. Carney and I Chanarin and Edward H. Reynolds},
  journal={British medical journal},
  volume={281 6247},
The neuropsychiatric states of 50 patients with vitamin B12 deficiency and 34 patients with folate deficiency presenting with megaloblastosis in a general hospital were examined and compared. Abnormalities of the nervous system were found in two-thirds of both groups. Peripheral neuropathy was the most common condition associated with vitamin B12 deficiency and affective disorder with folate deficiency. The proportions of patients with organic mental change were similar in the two groups… CONTINUE READING