The neuropsychiatry of Gilles de la Tourette syndrome: The état de l'art.

@article{Cavanna2018TheNO,
  title={The neuropsychiatry of Gilles de la Tourette syndrome: The {\'e}tat de l'art.},
  author={Andrea Eugenio Cavanna},
  journal={Revue neurologique},
  year={2018},
  volume={174 9},
  pages={
          621-627
        }
}
  • A. Cavanna
  • Published 8 August 2018
  • Psychology, Medicine
  • Revue neurologique
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Cross-cultural adaptation and psychometric evaluation of the French version of the Gilles de la Tourette Syndrome Quality of Life Scale (GTS-QOL)
TLDR
The cross-cultural adaptation and validation of this specific instrument will make it possible to assess health-related quality of life in French-speaking subjects with GTS and provide evidence of the good psychometric properties of the GTS-QOL-French.
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Providing an overview of the assessment, diagnosis, and pharmacological treatment of tics, this is a practical handbook designed for use in busy clinics by trainees and practitioners in a range of
Motor stereotypies in adult patients with Tourette syndrome
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TLDR
A comprehensive update on the multifarious aspects of the movement disorder and neuropsychiatry of GTS is provided and available treatment options are commented on.
Gilles de la Tourette syndrome
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Future research that integrates clinical and neurobiological data, including neuroimaging and genetics, is expected to reveal the pathogenesis of GTS at the neural circuit level, which may lead to targeted interventions.
The psychopathological spectrum of Gilles de la Tourette syndrome
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QoL profiles in children often reflect the impact of co-morbid attention-deficit and hyperactivity symptoms, which tend to improve with age, whereas adults’ perception of QoL seems to be more strongly affected by the presence of depression and anxiety.
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It is suggested that tic frequency and severity decline with age in a large proportion of patients (59-85%) and predictors of increased tic severity in adulthood include higher childhood tics severity, smaller caudate volumes and poorer fine motor control.
Health-Related Quality of Life in Gilles de la Tourette Syndrome: A Decade of Research
TLDR
This review focuses on the current evidence on the impact of GTS on patients' lives, mainly informed by studies using generic functional impairment and HR-QOL measures from the last decade, and expands on the new opportunities introduced by the recently developed GTS-specific HR- QOL scales.
Aripiprazole Improves Associated Comorbid Conditions in Addition to Tics in Adult Patients with Gilles de la Tourette Syndrome
TLDR
Evidence is provided that patients' decision making process for or against medical treatment is influenced by other factors than tic severity and QoL, which suggests that aripiprazole may improve associated comorbid conditions in addition to tics in patients with GTS.
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