The neuroprotective effects of caffeine in neurodegenerative diseases.

@article{Kolahdouzan2017TheNE,
  title={The neuroprotective effects of caffeine in neurodegenerative diseases.},
  author={Mahshad Kolahdouzan and Mazen J Hamadeh},
  journal={CNS neuroscience & therapeutics},
  year={2017},
  volume={23 4},
  pages={272-290}
}
Caffeine is the most widely used psychostimulant in Western countries, with antioxidant, anti-inflammatory and anti-apoptotic properties. In Alzheimer's disease (AD), caffeine is beneficial in both men and women, in humans and animals. Similar effects of caffeine were observed in men with Parkinson's disease (PD); however, the effect of caffeine in female PD patients is controversial due to caffeine's competition with estrogen for the estrogen-metabolizing enzyme, CYP1A2. Studies conducted in… CONTINUE READING
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