The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function.

@article{Filipsson2001TheNP,
  title={The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function.},
  author={Karin Filipsson and Martina Kvist-Reimer and Bo Ahr{\'e}n},
  journal={Diabetes},
  year={2001},
  volume={50 9},
  pages={1959-69}
}
The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is ubiquitously distributed in both the central and peripheral nervous systems and exerts a variety of effects. PACAP is a neuropeptide in pancreatic islets, where it has been suggested as a parasympathetic and sensory neurotransmitter. PACAP stimulates insulin secretion in a glucose-dependent manner, by an effect executed mainly through augmenting the formation of cAMP and stimulating the uptake of calcium… CONTINUE READING

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