The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions.

@article{Pralong2002TheNY,
  title={The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions.},
  author={François Pierre Pralong and Christine Gonzales and M. W. Voirol and Richard D Palmiter and H. Brunner and Rolf Christian Gaillard and Josiane Seydoux and Thierry Pedrazzini},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2002},
  volume={16 7},
  pages={712-4}
}
The orexigenic neurotransmitter neuropeptide Y (NPY) plays a central role in the hypothalamic control of food intake and energy balance. NPY also exerts an inhibition of the gonadotrope axis that could be important in the response to poor metabolic conditions. In contrast, leptin provides an anorexigenic signal to centrally control the body needs in energy. Moreover, leptin contributes to preserve adequate reproductive functions by stimulating the activity of the gonadotrope axis. It is of… CONTINUE READING
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