The neuropathology of vascular disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

@article{Richardson2012TheNO,
  title={The neuropathology of vascular disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).},
  author={Kathryn Richardson and Blossom C M Stephan and Paul G. Ince and Carol Brayne and Fiona E. Matthews and Margaret M. Esiri},
  journal={Current Alzheimer research},
  year={2012},
  volume={9 6},
  pages={687-96}
}
BACKGROUND Vascular disease is associated with increased risk of dementia. Vascular health worsens with age. We investigated the relationship between self-reported vascular disease and brain pathology. METHODS Brain donations to the population-based MRC Cognitive Function and Ageing Study (n=456, age range 66-103 years) were assessed using a standard protocol for Alzheimer's disease (AD) and cerebrovascular pathology. History of stroke, angina, diabetes, medicated hypertension and heart… CONTINUE READING

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