The neuropathology of Williams syndrome. Report of a 35-year-old man with presenile beta/A4 amyloid plaques and neurofibrillary tangles.

@article{Golden1995TheNO,
  title={The neuropathology of Williams syndrome. Report of a 35-year-old man with presenile beta/A4 amyloid plaques and neurofibrillary tangles.},
  author={Jeffrey Alan Golden and Gunnlauger Petur Nielsen and Barbara R Pober and Bradley T. Hyman},
  journal={Archives of neurology},
  year={1995},
  volume={52 2},
  pages={209-12}
}
OBJECTIVE To study neuropathologically Williams syndrome in a 35-year-old patient. METHODS Sections from multiple regions of the brain were examined with luxol fast blue and hematoxylineosin staining, and selected sections were stained with the silver impregnation technique (Bielschowsky technique) and Congo red. In addition, immunohistochemistry with monoclonal antibodies against glial fibrillary acidic protein, beta/A4 amyloid, paired helical filaments, and phosphorylated tau protein was… CONTINUE READING