The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse?

@article{Nieoullon2006TheNE,
  title={The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse?},
  author={A. Nieoullon and B. Canolle and F. Masmejean and B. Guillet and P. Pisano and S. Lortet},
  journal={Journal of Neurochemistry},
  year={2006},
  volume={98}
}
  • A. Nieoullon, B. Canolle, +3 authors S. Lortet
  • Published 2006
  • Biology, Medicine
  • Journal of Neurochemistry
  • EAAC1/EAAT3 is a transporter of glutamate (Glu) present at the post‐synaptic neuronal element, in opposition to the two other main transporters, GLAST/EAAT1 and GLT1/EAAT2, expressed at the excitatory amino acid (EAA) synapse by surrounding astrocytes. Although, in the adult, EAAC1/EAAT3 exhibits a rather low expression level and is considered to make a minor contribution to Glu removal from the synapse, its early expression during brain development, before the astrocytes are functional… CONTINUE READING
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