The neurological effects of ghrelin in brain diseases: Beyond metabolic functions

  title={The neurological effects of ghrelin in brain diseases: Beyond metabolic functions},
  author={Qian Jiao and Xixun Du and Yong Li and Bing Gong and Hong Jiang},
  journal={Neuroscience & Biobehavioral Reviews},
Ghrelin, a peptide released by the stomach that plays a major role in regulating energy metabolism, has recently been shown to have effects on neurobiological behaviors. Ghrelin enhances neuronal survival by reducing apoptosis, alleviating inflammation and oxidative stress, and accordingly improving mitochondrial function. Ghrelin also stimulates the proliferation, differentiation and migration of neural stem/progenitor cells (NS/PCs). Additionally, the ghrelin is benefit for the recovery of… CONTINUE READING
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