The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria

@article{Ambler2009TheNA,
  title={The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria},
  author={Michael T Ambler and Lilly MS Dubowitz and Ratree Arunjerdja and Eh Paw Hla and Kyaw Lay Thwai and Jacher Viladpai-nguen and Pratap Singhasivanon and Christine Luxemburger and François H Nosten and Rose McGready},
  journal={Malaria Journal},
  year={2009},
  volume={8},
  pages={207 - 207}
}
  • Michael T Ambler, Lilly MS Dubowitz, +7 authors Rose McGready
  • Published in Malaria Journal 2009
  • Medicine
  • BackgroundMefloquine and artesunate combination therapy is the recommended first-line treatment for uncomplicated malaria throughout much of south-east Asia. Concerns have been raised about the potential central nervous system (CNS) effects of both drug components and there are no detailed reports in very young children.MethodsChildren, aged between three months and five years, with acute uncomplicated Plasmodium falciparum malaria were randomized to either 7 days of artesunate monotherapy or… CONTINUE READING

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