The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.

@article{Sapolsky1986TheNO,
  title={The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.},
  author={Robert Morris Sapolsky and Lewis C. Krey and Bruce S. McEwen},
  journal={Endocrine reviews},
  year={1986},
  volume={7 3},
  pages={
          284-301
        }
}
AS RECENTLY as 1900, tuberculosis, influenza, and pneumonia were the leading causes of death in our country (1). For the most part, however, these infectious diseases, as well as those of poor hygiene or undernutrition, no longer plague us. Instead, we succumb most frequently to heart disease and cancer, diseases of slow degeneration (1). Most of all, unlike so many in the generations before us, we are in a position to age. Regardless of what else occurs, we age, we become more constrained by… 

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