The neurocircuitry of obsessive–compulsive disorder and disgust

@article{Husted2006TheNO,
  title={The neurocircuitry of obsessive–compulsive disorder and disgust},
  author={David S. Husted and Nathan Andrew Shapira and Wayne K. Goodman},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2006},
  volume={30},
  pages={389-399}
}

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Recent evidence implicating disgust in anxiety and OCD is examined, highlighting recent measurement and methodological improvements and an increased focus on disgust-related mechanisms that contribute to psychopathology, such as disgust-based learning and emotion regulation.

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The psychobehavioral aspects of OCD that are of importance on how the above ideas can be articulated are reviewed, and novel behavioral constructs for future investigations that may contribute to the face, predictive and construct validity of OCD animal models are identified.

Disgust Recognition in Obsessive-Compulsive Disorder: Diagnostic Comparisons and Posttreatment Effects

Support is provided for the presence of disgust recognition impairment in OCD, and preliminary evidence that disgust recognition impairments may improve with treatment is provided.

Neural Circuitry in Obsessive Compulsive Disorder: an fMRI Study of the Effect of IV Citalopram

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...

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Impaired recognition of disgust is consistent with the neurology of OCD and with the idea that abnormal experience of disgust may be involved in the genesis of obsessions and compulsions.

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