The neurobiology of zinc in health and disease

  title={The neurobiology of zinc in health and disease},
  author={Christopher J. Frederickson and Jae-Young Koh and Ashley I. Bush},
  journal={Nature Reviews Neuroscience},
The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout Roman and modern times (for example, as the American lotion named for its zinc ore, 'Calamine'). It is, therefore, somewhat ironic that zinc is a relatively late addition to the pantheon of signal ions in biology and medicine. However, the number of biological functions, health implications and pharmacological… CONTINUE READING