• DOI:10.1038/nrn1950
Corpus ID: 9373105

The neurobiology of itch

@article{Ikoma2006TheNO,
  title={The neurobiology of itch},
  author={A. Ikoma and M. Steinhoff and S. St{\"a}nder and G. Yosipovitch and M. Schmelz},
  journal={Nature Reviews Neuroscience},
  year={2006},
  volume={7},
  pages={535-547}
}

A. Ikoma, M. Steinhoff, +2 authors M. Schmelz

Published 2006

Medicine

Nature Reviews Neuroscience

The neurobiology of itch, which is formally known as pruritus, and its interaction with pain have been illustrated by the complexity of specific mediators, itch-related neuronal pathways and the central processing of itch. Scratch-induced pain can abolish itch, and analgesic opioids can generate itch, which indicates an antagonistic interaction. However, recent data suggest that there is a broad overlap between pain- and itch-related peripheral mediators and/or receptors, and there are… CONTINUE READING

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