The neurobiology of bipolar disorder

@article{Berns2003TheNO,
  title={The neurobiology of bipolar disorder},
  author={G. Berns and C. Nemeroff},
  journal={American Journal of Medical Genetics Part C: Seminars in Medical Genetics},
  year={2003},
  volume={123C}
}
  • G. Berns, C. Nemeroff
  • Published 2003
  • Medicine
  • American Journal of Medical Genetics Part C: Seminars in Medical Genetics
The neurobiology of bipolar disorder is reviewed. Bipolar disorder is associated with alterations in central nervous system (CNS) function from the level of large‐scale brain circuits to intracellular signal transduction mechanisms. Because of the broad spectrum over which these abnormalities appear, the causative effects are most likely present in the lowest common denominator of all of these systems. Current evidence points to subtle alterations in signal transduction that reverberate… Expand
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