The neurobiology of MMN and implications for schizophrenia
@article{Michie2016TheNO, title={The neurobiology of MMN and implications for schizophrenia}, author={Patricia T. Michie and Manuel S. Malmierca and Lauren Harms and Juanita Todd}, journal={Biological Psychology}, year={2016}, volume={116}, pages={90-97} }
41 Citations
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- Psychology, BiologyNeuropsychologia
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Event Related Potential Studies and Findings: Schizophrenia as a Disorder of Cognition
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The aim is to present the current state of research on neurophysiological underpinnings of schizophrenia that uses ERPs as a research tool and to point to major present and future trends within this field.
Reduced Auditory Mismatch Negativity Reflects Impaired Deviance Detection in Schizophrenia
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The use of the many-standards paradigm for deconstructing the constituent processes underlying the MMN is supported, with implications for the use of these translational measures to accelerate the development of new treatments that target perceptual and cognitive impairments in schizophrenia and related disorders.
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It is proposed to combine naturalistic stimulation, measures of speech–brain synchronization, and computational modeling of abstract linguistic knowledge and predictions to lead to a mechanistic understanding of the deficits underlying language related disorder(s) in schizophrenia.
Aberrant connectivity in auditory precision encoding in schizophrenia spectrum disorder and across the continuum of psychotic-like experiences
- Psychology, MedicineSchizophrenia Research
- 2020
While the results suggest continuity in backward connectivity alterations with psychotic-like experiences regardless of diagnosis, they also point to specificity for the schizophrenia spectrum disorder group in interhemispheric connectivity alterations.
Schizotypy and auditory mismatch negativity in a non-clinical sample of young adults
- Psychology, MedicinePsychiatry Research: Neuroimaging
- 2016
Cortical Microcircuit Mechanisms of Mismatch Negativity and Its Underlying Subcomponents
- Biology, PsychologyFrontiers in Neural Circuits
- 2020
It is hypothesized that SSA reflects adaptations occurring at synapses along the sensory-thalamocortical pathways, while DD depends on both SSA inherited from afferent inputs and resulting disinhibition of non-adapted neurons arising from the distinct physiology and wiring properties of local interneuronal subpopulations and NMDA-receptor function.
Cortical excitation-inhibition ratio mediates the effect of pre-attentive auditory processing deficits on interpersonal difficulties
- PsychologyProgress in Neuro-Psychopharmacology and Biological Psychiatry
- 2020
The findings support the growing body of literature pointing toward an excitation-inhibition imbalance that is central to psychosocial functioning across multi-dimensional spectrum disorders, such as autism and schizophrenia, and provides neurochemical indicators of the processes that underlie psychossocial dysfunction.
Decreased mismatch negativity and elevated frontal-lateral connectivity in first-episode psychosis.
- Psychology, MedicineJournal of psychiatric research
- 2021
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OBJECTIVE
It has been well established that schizophrenic patients have neurocognitive deficits, but it is not known how these deficits influence the daily lives of patients. The goal of this review…
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