The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence

  title={The neurobiology, clinical efficacy and safety of acamprosate in the treatment of alcohol dependence},
  author={B. Mason and C. Heyser},
  journal={Expert Opinion on Drug Safety},
  pages={177 - 188}
  • B. Mason, C. Heyser
  • Published 2010
  • Medicine
  • Expert Opinion on Drug Safety
  • Importance to the field: Acamprosate, marketed under the brand name Campral®, (Forest Pharmaceuticals, Inc., Saint Louis, MO, USA; Merck Sante s.a.s., Lyon, France) is an orally administered drug approved in the US and throughout much of the world for treating alcohol dependence. Its safety and efficacy have been demonstrated in a number of clinical trials worldwide and as with all pharmacotherapies for alcoholism, it is used in conjunction with psychosocial interventions. Areas covered in this… CONTINUE READING
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    Publications referenced by this paper.
    Treatment of alcohol-dependent outpatients with acamprosate: a clinical review.
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    Rationale for combining acamprosate and naltrexone for treating alcohol dependence.
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    Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis.
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    Acamprosate in alcohol dependence: a randomized controlled efficacy study in a standard clinical setting.
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    Acamprosate in the treatment of alcoholism: mechanisms and perspectives
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    Acamprosate in the treatment of alcohol dependence
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    Acamprosate in Alcohol Dependence: Implications of a Unique Mechanism of Action
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