The neurobiological basis of spontaneous alternation.

  title={The neurobiological basis of spontaneous alternation.},
  author={Robert Lalonde},
  journal={Neuroscience and biobehavioral reviews},
  volume={26 1},
  • Robert Lalonde
  • Published 2002 in Neuroscience and biobehavioral reviews
When placed in a T-maze, rats or mice possess a strong tendency of alternating arm choices on successive trials. The exploration of novel environmental stimuli is dependent on the integrity of limbic and non-limbic pathways, including the basal forebrain, the hippocampus, the thalamus, the prefrontal cortex, and the dorsal striatum, as well as the vestibular system and cerebellum. Neurochemical pathways using acetylcholine, gamma-amino-butyric acid, and dopamine in the septum and hippocampus… CONTINUE READING
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