The neural stem cell line CTX0E03 promotes behavioral recovery and endogenous neurogenesis after experimental stroke in a dose-dependent fashion.

@article{Stroemer2009TheNS,
  title={The neural stem cell line CTX0E03 promotes behavioral recovery and endogenous neurogenesis after experimental stroke in a dose-dependent fashion.},
  author={Paul Stroemer and Sara Patel and Andrew Hope and Cathy Oliveira and Kenny Pollock and John D. Sinden},
  journal={Neurorehabilitation and neural repair},
  year={2009},
  volume={23 9},
  pages={895-909}
}
BACKGROUND This study investigated behavioral recovery in rats following implanting increasing doses of CTX0E03 cells into the putamen ipsilateral to the stroke damage. Postmortem histological analysis investigated possible mechanisms of behavioral recovery. METHODS . At 4 weeks after middle cerebral artery occlusion (MCAO), rats were treated with 4500, 45,000, or 450,000 CTX0E03 cells or vehicle implanted into the putamen with testing on a battery of tasks preocclusion and postocclusion… CONTINUE READING
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