The neural correlates of orienting: an integration of fMRI and skin conductance orienting.

Abstract

In fMRI studies, the averaging of neural activity across multiple trials might obscure important psychophysiological subprocesses. The orienting response (OR) is a distinctive subprocess signalling the active orientation of attention towards potentially significant events. We sought to elucidate fMRI activity associated with visual stimuli that did or did not evoke simultaneously recorded electrodermal ORs (using customised skin conductance recording). 'With-OR' stimuli were associated with significant activity in the hippocampus, anterior cingulate and ventromedial prefrontal cortex. Averaged analysis revealed activity only in the expected visual circuits. Our results suggest that potentially significant stimuli (with-OR) activate different functional networks to familiar (without-OR) stimuli, and that orienting may therefore be an informative subprocess to consider in cognitive fMRI studies.

Extracted Key Phrases

5 Figures and Tables

Statistics

01020'02'04'06'08'10'12'14'16
Citations per Year

104 Citations

Semantic Scholar estimates that this publication has 104 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Williams2000TheNC, title={The neural correlates of orienting: an integration of fMRI and skin conductance orienting.}, author={Laverne McQuiller Williams and Michael J. Brammer and Donna L Skerrett and J Lagopolous and Chris J. Rennie and Krystian A. Kozek and Gloria Olivieri and Tony Peduto and E. Gordon}, journal={Neuroreport}, year={2000}, volume={11 13}, pages={3011-5} }