The neural circuitry of pain as explored with functional MRI.

  title={The neural circuitry of pain as explored with functional MRI.},
  author={Karen D. Davis},
  journal={Neurological research},
  volume={22 3},
Since the discovery in the early 1990s that magnetic resonance imaging (MRI) can be used for functional imaging of the human brain, the technique has been used to examine the contribution of thalamic and cortical areas to the human pain experience. In a series of studies in this laboratory, functional MRI (fMRI) of noxious heat-, cold-, and median nerve stimulation-evoked activations demonstrated the involvement of the thalamus and multiple cortical areas in pain. The cortical areas identified… CONTINUE READING

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