The neural cell adhesion molecule is involved in the metastatic capacity in a murine model of lung cancer.

@article{Campodnico2010TheNC,
  title={The neural cell adhesion molecule is involved in the metastatic capacity in a murine model of lung cancer.},
  author={Paola Bernadette Campod{\'o}nico and Elisa D Bal de Kier Joff{\'e} and Alejandro J. Urtreger and Lilia S Lauria and Jos{\'e} Mar{\'i}a Lastiri and Lydia In{\'e}s Puricelli and Laura Beatriz Todaro},
  journal={Molecular carcinogenesis},
  year={2010},
  volume={49 4},
  pages={386-97}
}
Neural cell adhesion molecule (NCAM) is involved in cell growth, migration, and differentiation. Its expression and/or polysialylation appear to be deregulated in many different cancer types. We employed the lung tumor cell line LP07, syngeneic in BALB/c mice to investigate the role of NCAM in malignant progression. LP07 cells express the three main NCAM isoforms, all of them polysialylated. This cells line, pretreated with an anti-NCAM antibody and inoculated intravenously (i.v.) into… CONTINUE READING
14 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…