The negative effect of platelet-rich plasma on the growth of human cells is associated with secreted thrombospondin-1.


OBJECTIVE Earlier studies have suggested that platelet-rich plasma (PRP) enhances oral wound healing because of its concentrated growth factors. Few studies have investigated whether negative regulators exist in the PRP and influence its biological effects on human wound healing. The aim of this study was to investigate whether PRP contains an angiogenesis… (More)
DOI: 10.1016/j.tripleo.2008.07.016


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