The need for neuroprotective therapies in Parkinson's disease: a clinical perspective.

@article{Poewe2006TheNF,
  title={The need for neuroprotective therapies in Parkinson's disease: a clinical perspective.},
  author={Werner Poewe},
  journal={Neurology},
  year={2006},
  volume={66 10 Suppl 4},
  pages={S2-9}
}
Slowing of disease progression remains a major unmet need in the treatment of Parkinson's disease (PD). Multiple factors are responsible for progression of disability in this disorder including worsening of cardinal motor features due to progressive nigral pathology, the evolution of poorly levodopa-responsive symptoms like freezing, postural instability and falls as well as motor complications of sustained treatment with levodopa. In addition, non-motor symptoms including cognitive decline… CONTINUE READING

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