The nature of the stimulation of the respiratory chain of rat liver mitochondria by glucagon pretreatment of animals.
@article{Halestrap1982TheNO, title={The nature of the stimulation of the respiratory chain of rat liver mitochondria by glucagon pretreatment of animals.}, author={Andrew P. Halestrap}, journal={The Biochemical journal}, year={1982}, volume={204 1}, pages={ 37-47 } }
1. Studies on the cytochrome spectra of liver mitochondria from control and glucagon-treated rats in State 4, State 3 and in the presence of uncoupler are reported. 2. The stimulation of electron flow between cytochromes c1 and c observed previously [Halestrap (1978) Biochem. J. 172, 399-405] was shown to be an artefact of Ca2+-induced swelling of mitochondria. 3. When precautions were taken to prevent such swelling, glucagon treatment was shown to enhance the reduction of cytochromes c, c1 and…
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