The nature of diene conjugation in human serum, bile and duodenal juice.

@article{Cawood1983TheNO,
  title={The nature of diene conjugation in human serum, bile and duodenal juice.},
  author={Pam Cawood and Dr. Gerald E. Wickens and Svein A. Iversen and Joan Marie Braganza and Thomas L Dormandy},
  journal={FEBS letters},
  year={1983},
  volume={162 2},
  pages={
          239-43
        }
}
Diene-conjugated lipids have been located by HPLC in serum, bile and duodenal juice. Whether esterified or not the same predominant fatty acid is responsible for most of the diene conjugation in all of these biological fluids. Initial attempts to generate this fatty acid in pure lipid by classical lipid peroxidation in vitro were unsuccessful. Ultraviolet irradiation of free fatty acids in the presence of protein produced diene-conjugated lipids similar to those found in vivo. The predominant… CONTINUE READING
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