The nature and effects of cortical microvascular pathology in aging and Alzheimer's disease.

@article{Bailey2004TheNA,
  title={The nature and effects of cortical microvascular pathology in aging and Alzheimer's disease.},
  author={Thomasina L Bailey and Claire B Rivara and Anne B. Rocher and Patrick R. Hof},
  journal={Neurological research},
  year={2004},
  volume={26 5},
  pages={573-8}
}
Age-related and amyloid-induced pathology of the cerebral microvasculature have been implicated as potential contributing factors to the pathogenesis of Alzheimer's disease (AD). The microvasculature plays a crucial role in maintaining brain homeostasis and deterioration of its integrity may have deleterious effects on brain function in AD, possibly leading to neurofibrillary degeneration, plaque formation, and cell loss. Brain vessels possess peculiar anatomical and physiological properties… CONTINUE READING

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