The nature and discriminatory value of urinary neutrophil gelatinase-associated lipocalin in critically ill patients at risk of acute kidney injury

@article{Glassford2013TheNA,
  title={The nature and discriminatory value of urinary neutrophil gelatinase-associated lipocalin in critically ill patients at risk of acute kidney injury},
  author={Neil John Glassford and Antoine Guillaume Schneider and Shengyuan Xu and Glenn Matthew Eastwood and Helen L Young and Leah Peck and Per Venge and Rinaldo Bellomo},
  journal={Intensive Care Medicine},
  year={2013},
  volume={39},
  pages={1714-1724}
}
Different molecular forms of urinary neutrophil gelatinase-associated lipocalin (NGAL) have recently been discovered. We aimed to explore the nature, source and discriminatory value of urinary NGAL in intensive care unit (ICU) patients. We simultaneously measured plasma NGAL (pNGAL), urinary NGAL (uNGAL), and estimated monomeric and homodimeric uNGAL contribution using Western blotting-validated enzyme-linked immunosorbent assays [uNGALE1 and uNGALE2] and their calculated ratio in 102 patients… CONTINUE READING
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