The natural history of surgically treated but radiotherapy-naïve nonfunctioning pituitary adenomas.

  title={The natural history of surgically treated but radiotherapy-na{\"i}ve nonfunctioning pituitary adenomas.},
  author={Eoin O'Sullivan and Conor Woods and Nigel Glynn and Lucy Ann Behan and Rachel K Crowley and Patrick O'kelly and Diarmuid Smith and Christopher J Thompson and Amar Agha},
  journal={Clinical endocrinology},
  volume={71 5},
BACKGROUND AND OBJECTIVES Transsphenoidal surgery is indicated for patients with nonfunctioning pituitary adenomas (NFPAs) causing compressive symptoms. Previous studies attempting to define the rate of recurrence/regrowth of surgically treated but radiation-naïve NFPAs were somewhat limited by selection bias and/or small numbers and/or lack of consistency of findings between studies. A better understanding of the natural history of this condition could allow stratification of recurrence risk… CONTINUE READING

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