The natural history of nonalcoholic fatty liver disease: a clinical histopathological study

@article{Harrison2003TheNH,
  title={The natural history of nonalcoholic fatty liver disease: a clinical histopathological study},
  author={S. A. Harrison and Sigurd J Torgerson and Paul Hideo Hayashi},
  journal={American Journal of Gastroenterology},
  year={2003},
  volume={98},
  pages={2042-2047}
}
OBJECTIVES:We aimed to define nonalcoholic steatohepatitis (NASH) histopathological change over time and to correlate changes with clinical characteristics.METHODS:We retrieved nonalcoholic fatty liver cases from our histopathology database covering 1985 to 2001. We also identified patients in clinic with NASH on biopsy >1 yr prior. All patients were evaluated and clinical data obtained in clinic. Those patients qualifying for NASH therapeutic trials underwent liver biopsy pretreatment. One… CONTINUE READING

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