The natural history of asymptomatic hepatitis B surface antigen carriers.

Abstract

OBJECTIVE To assess the long-term outcome in hepatitis B surface antigen (HBsAg) carriers who have normal liver function tests, focusing on survival and the development of severe liver disease and hepatocellular carcinoma. DESIGN Cohort study with a mean follow-up of 130 months. SETTING Liver clinic of a referral center. PATIENTS Ninety-two HBsAg… (More)

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