The natural course and the impact of therapies of cardiac involvement in the mucopolysaccharidoses.

@article{Fesslov2009TheNC,
  title={The natural course and the impact of therapies of cardiac involvement in the mucopolysaccharidoses.},
  author={Vlasta Fesslov{\'a} and Paola Corti and Giovanna Sersale and Attilio Maria Rovelli and Pierluigi Russo and Savina Mannarino and Gianfranco Butera and Rossella Parini},
  journal={Cardiology in the young},
  year={2009},
  volume={19 2},
  pages={170-8}
}
OBJECTIVE To analyze cardiac involvement and its progression in mucopolysaccharidoses, and to assess the short term impact of new therapeutic strategies. PATIENTS AND METHODS We studied echocardiographically 57 patients with various types of mucopolysaccharidoses, specifically types I, II, III, IV and VI, with a median age at the diagnosis of cardiac involvement of 5 years, following them for a median of 4.6 years, with a range from 0.9 to 21.2 years. We used a scoring system, along with the… CONTINUE READING