The natural 13C abundance of plasma glucose is a useful biomarker of recent dietary caloric sweetener intake.

  title={The natural 13C abundance of plasma glucose is a useful biomarker of recent dietary caloric sweetener intake.},
  author={Chad M. Cook and Amy L Alvig and Yu David Liu and Dale A. Schoeller},
  journal={The Journal of nutrition},
  volume={140 2},
There is a need for objective biomarkers of dietary intake, because self-reporting is often subject to bias. We tested the validity of a biomarker for the fraction of dietary carbohydrate (CHO) from cane sugar and high fructose corn syrup (C(4) sugars) using natural (13)C abundance of plasma glucose. In a randomized, single-blinded, crossover design, 5 participants consumed 3 weight-maintaining diets for 7 d, with a 2-wk washout between diet periods. Diets differed in the fraction of total CHO… CONTINUE READING


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