The natBr(p,x) (73,75)Se nuclear processes: a convenient route for the production of radioselenium tracers relevant to amino acid labelling.

@article{Fassbender2001TheN,
  title={The natBr(p,x) (73,75)Se nuclear processes: a convenient route for the production of radioselenium tracers relevant to amino acid labelling.},
  author={M Fassbender and Dawid de Villiers and Meiring Nortier and N van der Walt},
  journal={Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine},
  year={2001},
  volume={54 6},
  pages={905-13}
}
A possible route for the production of no-carrier-added (n.c.a.) 73Se (T(1/2) = 7.1 h) and 75Se (120 d) is introduced. D,L-2-Amino-4-([73Se]methyl-seleno) butanoic acid (D,L-[73Se]selenomethionine) with an overall radiochemical yield of > 40% could be prepared via a 3-step polymer-supported synthesis after successful separation of 73Se from KBr targets… CONTINUE READING