The nascent-polypeptide-associated complex alpha subunit regulates the polygalacturonases expression negatively and influences the pathogenicity of Sclerotinia sclerotiorum

  title={The nascent-polypeptide-associated complex alpha subunit regulates the polygalacturonases expression negatively and influences the pathogenicity of Sclerotinia sclerotiorum},
  author={Xiuli Li and Min Guo and Dafeng Xu and Fangxin Chen and Huajian Zhang and Yuemin Pan and Maomao Li and Zhimou Gao},
  pages={1130 - 1137}
Sclerotinia sclerotiorum is a necrotrophic plant-pathogenic fungus that infects more than 400 species of plants. In this study the nascent polypeptide-associated complex α subunit gene of S. sclerotiorum (SsNACα; accession No. XP_001593856.1) was cloned and characterized. The relative transcript expression of SsNACα at different morphological stages of asexual development of S. sclerotiorum were analyzed by quantitative real time PCR (qRT-PCR). RNAi-mediated gene silencing was successful for… 
The Notorious Soilborne Pathogenic Fungus Sclerotinia sclerotiorum: An Update on Genes Studied with Mutant Analysis
Key molecular findings on the unique biology and pathogenesis process of S. sclerotiorum are reviewed, focusing on genes that have been studied in depth using mutant analysis.
Pathogenic fungal protein-induced resistance and its effects on vegetable diseases
Experiments have demonstrated that exogenous application of fungal proteins could reduce Alternaria brassicicola-induced black spot severity on cabbage, Colletotrichum spp.-induced anthracnose on Chinese cabbage and cucumber, Rhizoctonia solani-induced damping-off on sweet pepper and Chinese cabbage, and powdery mildew on cucumber seedlings.


Type 2A phosphoprotein phosphatase is required for asexual development and pathogenesis of Sclerotinia sclerotiorum.
Reduced ERK (extracellular signal-regulated kinases)-like mitogen-activated protein kinase (MAPK) function conferred a reduction in NADPH oxidase and PP2A activity levels, suggesting a functional link between MAPK, reactive oxygen species, and PP1A activity in S. sclerotiorum.
The Sclerotinia sclerotiorum pac1 gene is required for sclerotial development and virulence.
  • J. Rollins
  • Biology
    Molecular plant-microbe interactions : MPMI
  • 2003
Based on results, pac1 appears to be necessary for the appropriate regulation of physiological processes important for pathogenesis and development of S. sclerotiorum.
Calcineurin is required for sclerotial development and pathogenicity of Sclerotinia sclerotiorum in an oxalic acid-independent manner.
Inhibition of calcineurin conferred a reduction in cell wall beta-1,3-glucan content and increased sensitivity to cell-wall-degrading enzymes and to the glucan synthase inhibitor caspofungin, Thus, calcinesurin plays a major role in both sclerotial development and pathogenesis of S. sclerOTiorum and, most likely, other phytopathogens.
MAPK regulation of sclerotial development in Sclerotinia sclerotiorum is linked with pH and cAMP sensing.
Sclerotial development is fundamental to the disease cycle of the omnivorous broad host range fungal phytopathogen Sclerotinia sclerotiorum and it is demonstrated that Smk1 is required for sclerOTial development.
Ss-Sl2, a Novel Cell Wall Protein with PAN Modules, Is Essential for Sclerotial Development and Cellular Integrity of Sclerotinia sclerotiorum
It is suggested that a protein, named Ss-Sl2, functions in both sclerotial development and cellular integrity of S. sclerOTiorum.
Molecular Characterization and in planta Detection of Sclerotinia sclerotiorum Endopolygalacturonase Genes
The isolation and characterization of three additional endoPG-encoding genes (pg5, pg6, and pg7) that belong to distinct phylogenetic groups are described and shown to have great similarity to that of the related necrotroph Botrytis cinerea.
Sclerotinia sclerotiorum (Lib.) de Bary: biology and molecular traits of a cosmopolitan pathogen.
This review summarizes current knowledge of mechanisms employed by the fungus to parasitize its host with emphasis on biology, physiology and molecular aspects of pathogenicity.
RNA silencing as a tool for exploring gene function in ascomycete fungi.