The name is bond — H bond

  title={The name is bond — H bond},
  author={T. W. Martin and Zygmunt S Derewenda},
  journal={Nature Structural Biology},
The hydrogen bond plays a critical role in diverse biological phenomena. Although discovered 90 years ago, the precise chemical nature of this unique interaction has remained in dispute. A recent Compton-scattering experiment, however, strongly supports a partially covalent picture of the hydrogen bond. 

Nature and strength of sulfur-centred hydrogen bonds: laser spectroscopic investigations in the gas phase and quantum-chemical calculations

The importance of Sulfur centred hydrogen bonds (SCHBs) cannot be underestimated given the current day knowledge of its non-covalent interactions prevalent in many biopolymers as well as in organic

It Is Important to Compute Intramolecular Hydrogen Bonding in Drug Design

The different ways of taking into account these interactions, mainly intramolecular hydrogen bonds, in docking calculations are explored, and their possible limitations and their suitable application domains are highlighted.

Theoretical studies of strong hydrogen bonds

Strong hydrogen bonds are analyzed and their specific characteristics are given. These interactions are compared with typical H-bonds. All analyses included are mainly based on ab initio and DFT

The topology of π···H hydrogen bonds

Unsaturated hydrocarbons are routinely used as proton acceptors because their π clouds possess a capacity to interact with Lewis acids and cationic species. Thus, in order to understand the formation

Structural aspects of the intermolecular hydrogen bond strength: H‐bonded complexes of aniline, phenol and pyridine derivatives

This short review is devoted to the description of the effect of the nature and the strength of intermolecular hydrogen bonds on structural properties of H-bonded complexes of aniline, phenol and

Neutron Crystallography for the Study of Hydrogen Bonds in Macromolecules

Specific examples of how neutron crystallography has contributed to structural biology, structure-based drug design; and the understanding of fundamental questions of reaction mechanisms are shown.

Nature of Amide Carbonyl−Carbonyl Interactions in Proteins

The intimate interaction between adjacent carbonyl groups is shown to arise primarily from n→π* electronic delocalization, which has implications for organic, biological, and medicinal chemistry.

The covalence and infrared spectra of cationic hydrogen bonds and dihydrogen bonds

A theoretical study of hydrogen bonds and dihydrogen bonds formed by ethyl cation, hydrocarbons and magnesium hydride is presented with calculations performed at the BHandHLYP/6-31G(d,p) level of

The Pnictogen Bond Formation Ability of Bonded Bismuth Atoms in Molecular Entities in the Crystalline Phase: A Perspective

A bismuth bond, a type of pnictogen bonding interaction, occurs in chemical systems when there is evidence of a net attractive interaction between the electrophilic region of a covalently or



C-H...O hydrogen bonding in biology.

50 Years of Hydrogen Bond Theory

The “hydrogen bond” or “hydrogen bridge” concept has proved to be one of the most useful structural concepts in modern science. The properties of substances containing hydrogen bonds depend on the

The occurrence of C-H...O hydrogen bonds in proteins.

This work describes an analysis of short C-H...O interactions in a sample of known protein structures representing different categories of tertiary folds and refined at a resolution of at least 2 A, and finds strong evidence that a large percentage of long C...O contacts constitute cohesive interactions.

Covalency of the Hydrogen Bond in Ice: A Direct X-Ray Measurement

Periodic intensity variations in the measured Compton profile anisotropies of ordinary ice $\mathrm{I}h$ correspond to distances of 1.72 and 2.85 \AA{}, which are close to the hydrogen bond length

The Shared-Electron Chemical Bond.

  • L. Pauling
  • Physics
    Proceedings of the National Academy of Sciences of the United States of America
  • 1928
It has been shown that in the case of two hydrogen atoms in the normal state brought near each other the eigenfunction which is symmetric in the positional coordinates of the two electrons corresponds to a potential which causes the two atoms to combine to form a molecule.

A Theory of Water and Ionic Solution, with Particular Reference to Hydrogen and Hydroxyl Ions

On the basis of the model of the water molecule derived from spectral and x-ray data and a proposed internal structure for water, the following properties of water and ionic solutions have been

On the Structure of Native, Denatured, and Coagulated Proteins.

  • A. MirskyL. Pauling
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1936
The theory provides a simple structural interpretation not only of the phenomena connected with denaturation and coagulation which are usually discussed but also of others, such as the availability of groups, the entropy of denaturation, the effect of ultra-violet light, the heat of activation and its dependence on pH, coagulating through dehydration, etc.